Being smart allows you to figure things out.
The other day I was reading something and came across an acronym I'd never see before: HNIC.
Could mean anything, but from the context, I figured out that it means "High Nigger in Charge."
And today, I saw an acronym that read "MENA." Well, from the context, it was clear that meant Middle East-North Africa.
No glossary necessary...if you're smart.